TPM algorithm was developed by Fahad Saeed at the Epithelial Systems Biology Laboratory, National Heart, Lung, and Blood Institute in Bethesda, Maryland USA.
If you use this algorithm please cite the following paper:
Fahad Saeed, Trairak Pisitkun, Mark Knepper and Jason D Hoffert, “Mining Temporal Patterns from iTRAQ Mass Spectrometry (LC-MS/MS) Data”, The Proceedings of the ISCA 3rd International Conference on Bioinformatics and Computational Biology (BiCoB), Vol 1. pp 152-159 New Orleans, Louisiana, USA, March 23-25, 2011 (ISBN: 978-1-880843-81-9)
Link to full paper: arXiv:1104.5510v1
Status
The method development for this work is complete